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Center for hemophilia with a laboratory for the detection of coagulative disorders

Telephone: +38733567316
e-mail: koagulacija@ztmfbih.ba
WORKING HOURS FOR TAKING BLOOD SAMPLES: every working day 8:00 - 10:00
WORKING HOURS FOR ISSUEING REPORTS: every working day 13:30-14:30
Taking samples and issuing reports is done in the outpatient clinic no. 102 on the first floor.
Note: Appointments must be scheduled for coagulopathy, thrombophilia and platelet tests.
For all information and scheduling, you can call us at: 033 567-316

LABORATORY TEAM:
  • 1 ljekar - specialist transfuziologist-head of laboratory
  • 1 ljekar - specialist transfusionist
  • 1 ing. medical-lab diagnostics
  • 1 graduated biologist
  • 1 medical technician
Functionality of the laboratory for the detection of coagulative disorders
  • Diagnostics of innate and acquired coagulopathy
  • Diagnostics of inherited and acquired thrombophilia
  • Control and monitoring of oerial anticoagulant therapy
  • Control and monitoring of women with thrombophilia in pregnancy
  • Participation in scientific projects
  • International cooperation
LABORATORY RESEARCH
    Examination of hemostasis disorders
    The patients are examined
    1. Who have a tendency to bleed - hemorrhagic syndromes
    • Born or acquired vasculopathy disorders
    • Functional disorders and platelet count
    • Absence of coagulation factor or presence of factor inhibitors
    2. Patients with a tendency towards thrombosis
    • Patients with manifest thrombosis or
    • Patients who have an increased risk of developing thrombosis
    • Women with complications of pregnancy (repeated loss of pregnancy or venous thrombosis)
TESTS:
    1. Hemostasis screening tests (PT, APTT, TT, platelet count, fibrinogen and euglobulin fibrinolysis test).
    2. Coagulation factor activity (fibrinogen, FII, FV, FVII, FVIII, FIX, FX, FXI, FXII for diagnosis of innate and acquired coagulopathy
    3. Activity and concentration of von Willebrand's antigen concentration as well as platelet aggregation induced by ristocetin for the diagnosis of von Willebrand's disease
    4. Detection of presence and differential diagnosis of coagulation inhibitors (coagulation factor inhibitors and lupus anticoagulants)
    5. Tests for Diagnosis of Disseminated Intravascular Coagulation (DIK)
    6. Thrombocyte function assay (platelet aggregation induced by collagen, ADP, ristocetin)

    Test scheduling and other information: +387 33 567 316

Laboratory diagnosis of thrombophilia
    More than 1800 patients with thromboembolic complications and women with complications in pregnancy related to repeated pregnancy loss and / or venous thromboembolism have been tested at the Department. These patients are obliged to:
    1. screening hemostasis tests (PT, APTT, platelet count, fibrinogen)
    2. Specific high-priority tests to prove the presence of thrombophilia

    - the biological activity of antithrombin III, - protein C, - protein S, - presence of APC-R Lupus anticoagulant

    3. Depending on the results obtained, additional PCR analysis, genetic mutations (polymorphisms) on the FV (Factor V), FII (Factor II) genes, as well as on the enzyme gene MTHFR (methylentetrahydrofolate reductase)

    For all the analyzes that are necessary for the diagnosis of innate and acquired thrombophilia, samples from the patient are taken in scheduled times, which facilitates and accelerates the diagnosis procedure


    Test scheduling and other information: +387 33 567 316

Oral anticoagulant therapy
    A special segment of activity refers to the monitoring of patients with anticoagulant therapy. For these patients, there is organized control that is performed every working day, which implies:

    - Determination of prothrombin time (INR)
    - Determine the dose of the drug in relation to the obtained results
    - monitoring and preparation of these patients for all planned invasive tests, tooth extraction, surgical interventions


Test scheduling and other information: +387 33 567 316

INTERNATIONAL COOPERATION

Our Laboratory is a member of the external control prescribed by the World Health Organization's International External Quality Assessment Scheme